Table 1 Study demographic characteristics of never users and ever users of calcium channel blocking drugs at study baseline
Calcium channel blocker use | |||
|---|---|---|---|
Never used (N = 46,904) | Used (N = 3853) | p valuea | |
Age at baseline | 54.5 (48.0–61.0) | 60.2 (55.0–66.0) | <0.0001 |
Age at menarche | 12.7 (12.0–13.0) | 12.4 (11.5–13.0) | <0.0001 |
Race | <0.0001 | ||
Non-Hispanic White | 39,705 (85) | 2748 (71) | |
Non-Hispanic Black | 3655 (8) | 797 (21) | |
Hispanic | 2311 (5) | 197 (5) | |
Other | 1219 (3) | 110 (3) | |
Missing | 14 (<1) | 0 (<1) | |
Body mass index | <0.0001 | ||
<25 | 18,588 (40) | 786 (20) | |
25.0–29.9 | 14,953 (32) | 1166 (30) | |
30.0–34.9 | 7839 (17) | 944 (25) | |
35.0+ | 5508 (12) | 956 (25) | |
Missing | 16 (<1) | 1 (<1) | |
Menopause status | <0.0001 | ||
Pre menopause | 14,254 (30) | 461 (12) | |
Post menopause | 32,332 (69) | 3381 (88) | |
Missing | 318 (1) | 11 (<1) | |
Ever pregnant | <0.0001 | ||
No | 5947 (13) | 407 (11) | |
Yes | 40,935 (87) | 3445 (89) | |
Missing | 22 (<1) | 1 (<1) | |
Ever used hormone replacement therapy | <0.0001 | ||
No | 26,193 (56) | 1532 (40) | |
Yes | 20,561 (44) | 2313 (60) | |
Don’t know/missing | 150 (<1) | 8 (<1) | |
Ever diagnosed with cancerb | 0.0009 | ||
No | 44,612 (95) | 3613 (94) | |
Yes | 2241 (5) | 230 (6) | |
Don’t know/missing | 51 (<1) | 10 (<1) | |
Smoking status | <0.0001 | ||
Never smoked | 26,441 (56) | 2045 (53) | |
Past smoker | 16,604 (35) | 1487 (39) | |
Current smoker | 3845 (8) | 318 (8) | |
Don’t know/missing | 14 (1) | 3 (<1) | |