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Table 3 Association between APOBEC3B copy number and clinicopathologic features of breast cancersa

From: Germline APOBEC3B deletion is associated with breast cancer risk in an Asian multi-ethnic cohort and with immune cell presentation

Clinical variables Data available N (%) A3B wt/wt A3B del/wt A3B del/del P value
Age (year) 1451 (100) 50.0 ± 7.4 51.0 ± 7.8 51.0 ± 7.1 0.23b
Grade 1/2/3 (%) 1140 (78.6) 14/51/36 11/54/36 14/51/36 0.76c
Size (cm) 1220 (84.1) 2.5 ± 2.5 2.5 ± 2.2 2.5 ± 1.7 0.93b
Node + (%) 1308 (90.1) 47.7 44.4 39.7 0.17c
ER+ (%) 1370 (94.4) 65.8 68.7 65.2 0.49c
PR+ (%) 1346 (92.8) 51.1 51.0 47.5 0.65c
HER2 (%) 1328 (91.5) 49.0 44.6 40.4 0.09c
TNBC (%) 1240 (87.7) 12.5 12.2 17.5 0.17c
  1. A3B wt/wt no deletion, A3B del/wt one-copy deletion, A3B del/del two-copy deletion, ER+ estrogen receptor positive, PR+ progesterone receptor positive, HER2 human epithelial receptor 2, TNBC triple-negative breast cancer
  2. aUnless otherwise specified, data are presented in median ± interquartile range
  3. bANOVA
  4. cChi-squared test