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Table 1 Demographic characteristics and known breast cancer risk factors of study participantsa

From: Germline APOBEC3B deletion is associated with breast cancer risk in an Asian multi-ethnic cohort and with immune cell presentation

Category

Cases (N = 1451)

Controls (N = 1442)

P value

Demographic factors

 Age (year)

51.6 ± 7.5

51.4 ± 7.3

0.49b

Reproductive risk factors

 Age at menarche (year)

13.0 ± 1.5

12.9 ± 1.4

0.05b

 Age at menopause (year)d

49.4 ± 4.5

49.3 ± 4.4

0.54b

 Number of live birthse

2.9 ± 1.3

3.2 ± 1.5

<0.01b

 Age at first live birth (year)e

26.4 ± 5.0

27.5 ± 4.9

<0.01b

Other risk factors

 First-degree relatives with breast cancer (%)

13.2

11.0

0.08c

 First- or second-degree relatives with breast cancer (%)

19.6

17.8

0.23c

 Oral contraceptive (%)f

28.2

31.5

0.06c

 Hormone replacement therapy (%)f

9.5

9.8

0.80c

  1. aUnless otherwise specified, data are presented in mean ± standard deviation
  2. b t test
  3. cChi-squared test
  4. dAmong postmenopausal women
  5. eAmong parous women
  6. fEver user