The distribution of ductal carcinoma in situ (DCIS) grade in 4232 women and its impact on overdiagnosis in breast cancer screening

Table 5 Overdiagnosis estimates by two different definitions

	Low-grade DCIS	Intermediate-grade DCIS	High-grade DCIS
Population perspective	60 %	56 %	45 %
Individual perspective	61 %	57 %	45 %
Individual perspective by age group
50–55	58 %	46 %	21 %
55–60	62 %	55 %	29 %
60–65	66 %	64 %	50 %
65–70	49 %	52 %	61 %
70–75	54 %	58 %	66 %

Population perspective: the proportion of all cancers ever diagnosed in women of the screening age and over (50–100 years) that are overdiagnosed. Individual perspective: the proportion of all cancers ever diagnosed in women of the screening age (50–75 years) that are overdiagnosed. Low-grade DCIS: DCIS with a low malignant potential. Intermediate-grade DCIS: DCIS with an intermediate malignant potential. High-grade DCIS: DCIS with a high malignant potential
DCIS ductal carcinoma in situ

ISSN: 1465-542X