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Table 2 Association of four-category background parenchymal uptake at molecular breast imaging with breast cancer

From: Background parenchymal uptake on molecular breast imaging as a breast cancer risk factor: a case-control study

BPU level Breast cancer casesa (n = 62) Controlsa (n = 179) ORb p-trend AUCb
Reader 1     0.007 0.62 (0.55–0.69)
 Photopenic 5 (8) 26 (15) 0.8 (0.3–2.3)   
 Minimal to mild 35 (56) 124 (69) 1.0   
 Moderate 12 (19) 12 (7) 3.6 (1.4–8.9)   
 Marked 10 (16) 17 (9) 3.0 (1.1–8.4)   
Reader 2     <0.001 0.63 (0.56–0.70)
 Photopenic 2 (3) 18 (10) 0.5 (0.1–2.3)   
 Minimal to mild 36 (58) 132 (74) 1.0   
 Moderate 13 (21) 17 (9) 3.9 (1.6–9.7)   
 Marked 11 (18) 12 (7) 6.2 (2.0–19.0)   
  1. BPU background parenchymal uptake
  2. aNumbers in parentheses are percentages
  3. bNumbers in parentheses are 95 % CIs. OR is adjusted for body mass index