Table 3 Effect modification by age on the association between infertility, fertility treatment and mammographic density
Ages 40–49 | Ages 50–69 | |||
|---|---|---|---|---|
N | MD (95 % CI) | N | MD (95 % CI) | |
Absolute dense volume, cm3 | ||||
No infertility | 13,720 | −1.08 (−2.74 to 0.59) | 20,640 | −1.05 (−2.15 to 0.04) |
No hormone treatment | 2000 | 0.00 (Reference) | 5948 | 0.00 (Reference) |
Hormonal treatmenta | 618 | −2.81 (−5.63 to 0.01) | 1429 | 0.93 (−1.47 to 3.34) |
COS for IVF/ICSIb | 1122 | 2.57 (−0.12 to 5.25) | 1576 | 4.96 (0.96 to 8.96) |
Absolute non-dense volume, cm3 | ||||
No infertility | 13,720 | −11.9 (−24.6 to 0.7) | 20,640 | −1.8 (−9.6 to 6.0) |
No hormone treatment | 2000 | 0.0 (Reference) | 5948 | 0.0 (Reference) |
Hormonal treatmenta | 618 | 6.9 (−17.6 to 31.4) | 1429 | 17.2 (−0.9 to 35.2) |
COS for IVF/ICSIb | 1122 | −3.5 (−23.9 to 16.8) | 1576 | 11.7 (−13.7 to 37.1) |
Percent dense volume, pp | ||||
No infertility | 13,720 | 0.10 (−0.16 to 0.36) | 20,640 | −0.26 (−0.48 to −0.04) |
No hormone treatment | 2000 | 0.00 (Reference) | 5948 | 0.00 (Reference) |
Hormonal treatmenta | 618 | −0.12 (−0.60 to 0.35) | 1429 | −0.24 (−0.73 to 0.24) |
COS for IVF/ICSIb | 1122 | 0.23 (−0.17 to 0.64) | 1576 | 0.48 (−0.16 to 1.11) |