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Table 4 Performance of the five-gene model in predicting diagnosis in the independent validation cohort of 230 core biopsies

From: A five-gene reverse transcription-PCR assay for pre-operative classification of breast fibroepithelial lesions

 

Diagnosis from pathological report

 

Predicted outcome from the five-gene assay

Fibroadenomas

Phyllodes tumors

 

Fibroadenomas

179

7

NPV = 0.962

Phyllodes tumors

10

34

PPV = 0.773

 

Spec = 0.947

Sen = 0.829

 
  1. The five-gene assay has an overall accuracy of 92.6 %, with a sensitivity (sen) of 82.9 % and specificity (spec) of 94.7 %. The positive predictive value (PPV) and negative predictive value (NPV) are 77.3 % and 96.2 % respectively
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Breast Cancer Research

ISSN: 1465-542X

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