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Fig. 2 | Breast Cancer Research

Fig. 2

From: Lack of cortistatin or somatostatin differentially influences DMBA-induced mammary gland tumorigenesis in mice in an obesity-dependent mode

Fig. 2

Mammary gland tumor formation induced by 7, 12 dimethylbenz[α]anthracene (DMBA) in wild-type (WT), cortistatin (CORT)-knockout (KO) and somatostatin (SST)-KO mice on a low fat (LF)/high fat (HF) diet. a Tumor incidence (represented as percentage of mice with tumors), b tumor latency in days, c tumor multiplicity, and d tumor burden (n = 23–43/group). Values represent percentages (for tumor incidence) or mean ± standard error of the mean: *p <0.05, **p <0.01, ***p <0.001 for significant differences between groups analyzed by the Fisher or Mann–Whitney post-hoc test. n.d. not detected

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