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Table 2 Univariate and multivariate logistic regression models of clinical factors and median lymphocyte density

From: Computational pathology of pre-treatment biopsies identifies lymphocyte density as a predictor of response to neoadjuvant chemotherapy in breast cancer

   Univariate Multivariate
Variable Categories Odds ratio 95 % CI P value Observations Odds ratio 95 % CI P value Observations
Age Continuous 0.99 0.97, 1.02 0.6 755 0.99 0.96-1.02 0.44 406
Tumour size ≤50 mm, >50 mm 0.89 0.54, 1.48 0.66 755 0.68 0.27-1.75 0.43 406
Node status Negative, positive 0.8 0.54, 1.18 0.25 755 0.56 0.31-1.00 0.05 406
Grade 1, 2, 3 3.98 2.38, 6.67 <0.00001 588 3.62 1.74-7.52 0.0006 406
ER status Negative, positive 0.26 0.17, 0.38 <0.00001 755 0.3 0.17-0.53 0.00004 406
HER2 status Negative, positive 1.6 1.03, 2.50 0.04 665 1.81 0.97-3.37 0.06 406
Median lymphocyte density Continuous 4.46 2.34, 8.50 <0.00001 614 2.42 1.08-5.40 0.03 406
  1. ER oestrogen receptor; HER2 human epidermal growth factor receptor 2