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Table 2 Univariate and multivariate logistic regression models of clinical factors and median lymphocyte density

From: Computational pathology of pre-treatment biopsies identifies lymphocyte density as a predictor of response to neoadjuvant chemotherapy in breast cancer

  

Univariate

Multivariate

Variable

Categories

Odds ratio

95 % CI

P value

Observations

Odds ratio

95 % CI

P value

Observations

Age

Continuous

0.99

0.97, 1.02

0.6

755

0.99

0.96-1.02

0.44

406

Tumour size

≤50 mm, >50 mm

0.89

0.54, 1.48

0.66

755

0.68

0.27-1.75

0.43

406

Node status

Negative, positive

0.8

0.54, 1.18

0.25

755

0.56

0.31-1.00

0.05

406

Grade

1, 2, 3

3.98

2.38, 6.67

<0.00001

588

3.62

1.74-7.52

0.0006

406

ER status

Negative, positive

0.26

0.17, 0.38

<0.00001

755

0.3

0.17-0.53

0.00004

406

HER2 status

Negative, positive

1.6

1.03, 2.50

0.04

665

1.81

0.97-3.37

0.06

406

Median lymphocyte density

Continuous

4.46

2.34, 8.50

<0.00001

614

2.42

1.08-5.40

0.03

406

  1. ER oestrogen receptor; HER2 human epidermal growth factor receptor 2
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Breast Cancer Research

ISSN: 1465-542X

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