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Table 1 Selected characteristics of women in the BREAST Stamp Project with benign breast disease, stratified by menopausal status

From: Circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: a cross-sectional study of women with benign breast disease

Characteristic Premenopausal: n = 155 Postmenopausal: n = 73  
age = 40–55 (median 47) years age = 44–64 (median 57) years
  Number Percent Number Percent P t
Age at biopsy (years)
 40–44 53 34.2 1* 1.4 <0.001
 45–49 64 41.3 2 2.7  
 50–54 37 23.9 21 28.8  
 55–59 1 0.6 24 32.9  
 60–65 0 0 25 34.2  
Race/Ethnicity
 White, non-Hispanic 147 94.8 67 91.8 0.37
 Other 8 5.2 6 8.2  
Body mass index (kg/m2)
 <25 84 54.2 32 43.8 0.34
 25.0–29.9 35 22.6 21 28.8  
 ≥30 36 23.2 20 27.4  
Age at menarche (years)
 ≤12 56 36.1 30 41.1 0.36
 13 60 38.7 21 28.8  
 ≥14 38 24.5 21 28.8  
 Missing 1 0.6 1 1.4  
Parity
 Nulliparous 41 26.4 17 23.3 0.12
 1 13 8.4 14 19.2  
 2 65 41.9 29 39.7  
 ≥3 36 23.2 13 17.8  
Age at first birth (years)
 <25 37 23.9 33 45.2 0.01
 25–29 44 28.4 14 19.2  
 ≥30 33 21.3 9 12.3  
Oral contraceptive use
 Never 23 14.8 10 13.7 0.82
 Ever 132 85.2 63 86.3  
Type of menopause
 Natural ~ ~ 53 72.6 ~
 Surgical ~ ~ 3 4.1  
 Type unknown ~ ~ 17 23.3  
Age at menopause (years)
 ≤45 ~ ~ 21 28.8 ~
 46–49 ~ ~ 13 17.8  
 50–52 ~ ~ 19 26  
 ≥53 ~ ~ 13 17.8  
 Unknown ~ ~ 7 9.6  
Any menopausal hormone therapy usea
 Never 135 87.1 49 67.1 <0.001
 Ever 19 12.3 24 32.9  
 Missing 1 0.6 0 0  
Cigarette smoking (100+ cigarettes/lifetime)
 Never 83 53.5 28 38.4 0.07
 Former 55 35.5 31 42.5  
 Current 10 6.5 10 13.7  
 Missing/Unknown 7 4.5 4 5.5  
Family history of breast cancerb
 0 114 73.5 52 71.2 0.96
 ≥1 41 26.5 19 26  
 Missing 0 0 2 2.7  
  1. aData on any use of menopausal hormone therapy (MHT) missing for one premenopausal woman, and current MHT use missing for one postmenopausal woman who reported ever use. bWomen with at least one first degree relative with a diagnosis of breast cancer. P t is the value for testing for differences in distribution by menopausal status using the chi square (Χ 2) test or Fisher's exact test when the number for a category was <5. *This woman experienced natural menopause