Fig 5
From: Lymphocyte depletion and repopulation after chemotherapy for primary breast cancer
Differences in chemotherapy regimen correlate with the extent of B cell and CD4+ T cell depletion and with the dynamics of B cell recovery. Patients received anthracycline-based chemotherapy (EC/FEC, open boxes; n = 39) or anthracyclines followed by taxanes (EC + TAX, filled boxes; n = 44). Peripheral B cell and CD4+ T cells were quantified by multi-parameter flow cytometry either before chemotherapy (pre) or at time-points after the end of chemotherapy (2 weeks [2w]; 3, 6 or 9 months [3m, 6m, 9m]). Data are shown as absolute counts (left panels) or relative to the matched pre-chemotherapy level (right panels). Boxes represent 50 % of the data, with medians (lines), interquartile ranges (whiskers) and individual outliers (circles). *p < =0.05 **p < 0.01