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Table 1 Frequency of site-specific metastasis among metastatic breast cancer patients

From: Breast cancer brain metastases: biology and new clinical perspectives

Site of relapse

Brain (%)

Bone (%)

Lung (%)

Liver (%)

Pleura (%)

Autopsy casesa

     

 Median

21

71

71

62

50

 Range

15–35

50–74

60–80

50–71

35–80

All subtypesb

12–17

48–62

23–32

15–27

7–31

Luminal A

8–15

65–67

6–7

12–29

15–28

Luminal B

11

58–71

24–30

4–32

11–35

TNBC/basal

25–27

17–39

40–43

13–21

3–29

HER2-positive

11–20

61–62

15–42

22–44

0–32

  1. aMedian value and range from seven different studies reported by [85, 86]
  2. bSummarized data from the studies reported in [11, 12, 14]
  3. HER human epidermal growth factor receptor, TNBC triple-negative breast cancer