Fig. 3

Mammosphere-forming efficiency of MDA-MB-231 and SUM159 cells treated with Cetuximab +/- Ixabepilone. Mammosphere formation (%) of MDA-MB-231 (a) and SUM159 (b) cells was compared between control (no treatment) and Cetuximab treatment at concentrations of 10 μg/ml, 30 μg/ml, 50 μg/ml or between Ixabepilone (5 nM) and Ixabepilone (5 nM) + Cetuximab treatment at 10 μg/ml, 30 μg/ml, 50 μg/ml. The Mann–Whitney U test was used to determine the p values. Data represent the mean of three independent experiments. N.S. not significant