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Table 2 Gene expression in continuous diet DMBA-induced tumors

From: Puberty-specific promotion of mammary tumorigenesis by a high animal fat diet

  

Fold regulation (compared with LFD)

Symbol

Description

HFD-earlya

HFD-late

Ntf3

Neurotrophin 3

53.4

6.3

Trp53

Transformation related protein 53

1.6

NS

Ccnd2

Cyclin D2

3.5

3.5

Ctnnb1

Catenin (cadherin associated protein), beta 1

1.8

−3.6

Brca1

Breast cancer 1

1.8

−1.5

Apaf1

Apoptotic peptidase activating factor 1

1.8

1.3

Bmp7

Bone morphogenetic protein 7

3.2

NS

Bmp10

Bone morphogenetic protein 10

−3.4

NS

  1. DMBA 7,12-dimethylbenz[a]anthracene HFD high saturated animal fat diet, LFD low-fat diet
  2. p < 0.05 for all genes listed, except NS = no significant change [n = 4 tumors per diet group (LFD, HFD-early, HFD-late)]
  3. aHFD-early data from Zhao et al. [6]