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Fig. 1 | Breast Cancer Research

Fig. 1

From: Puberty-specific promotion of mammary tumorigenesis by a high animal fat diet

Fig. 1

Experimental design and Kaplan-Meier plot of 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumors. a BALB/c mice were started on a high saturated animal fat diet (HFD) or a low-fat diet (LFD) at 3 weeks old. Mice were switched from HFD to LFD and from LFD to HFD at 9 weeks old. DMBA was administered weekly from ages 5 to 8 weeks. Tumor incidence was observed. b–e Kaplan-Meier plots of tumor incidence. Time = number of days after last DMBA treatment (HFD mice, n = 101; LFD mice, n = 90; HFD-LFD mice, n = 42; LFD-HFD mice, n = 45). b HFD-LFD vs. HFD. c LFD-HFD vs. LFD. d LFD-HFD vs. HFD-LFD. e LFD vs. HFD

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