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Table 4 Association of copy number variations with clinical variables

From: Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response

A. Pathological complete remission (pCR)
Gene pCR (number) No pCR (number) pCR and CNV (number) No pCR and CNV (number) P value Adjusted p value
TTK 23 28 0 8 0.02 0.95
TP53BP2 23 28 4 15 0.06 0.95
SNAI2 23 28 1 8 0.09 1.00
STK3 23 28 1 8 0.09 1.00
ABL2 23 28 7 3 0.11 1.00
B. Relapse
Gene Relapse (number) No relapse (number) Relapse and CNV (number) No relapse and CNV (number) P value Adjusted p value
SNAI2 8 32 4 1 0.03 0.14
MAPK15 8 32 5 3 0.06 0.14
TTN 8 32 0 9 0.07 0.65
PARP10 8 32 6 4 0.08 0.14
STYK1 8 32 0 7 0.11 0.77
C. BRCA proficiency
Gene BRCA mut/meth (number) BRCA proficient (number) BRCA mut/meth and CNV (number) BRCA proficient and CNV (number) P value Adjusted p value
IFT81 27 24 1 8 0.001 0.36
SNAI2 27 24 1 8 0.01 0.36
TNFAIP3 27 24 9 0 0.01 0.88
 PLCXD3 27 24 5 11 0.02 1.00
CCNB2 27 24 10 1 0.06 1.00
  1. mut/meth mutated/methylated, CNV copy number variation