TY - JOUR AU - Chin, L. AU - Andersen, J. N. AU - Futreal, P. A. PY - 2011 DA - 2011// TI - Cancer genomics: from discovery science to personalized medicine JO - Nat Med VL - 17 UR - https://doi.org/10.1038/nm.2323 DO - 10.1038/nm.2323 ID - Chin2011 ER - TY - JOUR AU - Simó-Riudalbas, L. AU - Esteller, M. PY - 2014 DA - 2014// TI - Cancer genomics identifies disrupted epigenetic genes JO - Hum Genet VL - 133 UR - https://doi.org/10.1007/s00439-013-1373-5 DO - 10.1007/s00439-013-1373-5 ID - Simó-Riudalbas2014 ER - TY - JOUR AU - Tsai, H. C. AU - Baylin, S. B. PY - 2011 DA - 2011// TI - Cancer epigenetics: linking basic biology to clinical medicine JO - Cell Res VL - 21 UR - https://doi.org/10.1038/cr.2011.24 DO - 10.1038/cr.2011.24 ID - Tsai2011 ER - TY - JOUR AU - Berdasco, M. AU - Esteller, M. PY - 2010 DA - 2010// TI - Aberrant epigenetic landscape in cancer: how cellular identity goes awry JO - Dev Cell VL - 19 UR - https://doi.org/10.1016/j.devcel.2010.10.005 DO - 10.1016/j.devcel.2010.10.005 ID - Berdasco2010 ER - TY - JOUR AU - Brooks, J. AU - Cairns, P. AU - Zeleniuch-Jacquotte, A. PY - 2009 DA - 2009// TI - Promoter methylation and the detection of breast cancer JO - CCC VL - 20 ID - Brooks2009 ER - TY - JOUR AU - Delpu, Y. AU - Cordelier, P. AU - Cho, W. C. AU - Torrisani, J. PY - 2013 DA - 2013// TI - DNA methylation and cancer diagnosis JO - Int J Mol Sci VL - 14 UR - https://doi.org/10.3390/ijms140715029 DO - 10.3390/ijms140715029 ID - Delpu2013 ER - TY - JOUR AU - Garcia-Gimenez, J. L. AU - Sanchis-Gomar, F. AU - Lippi, G. AU - Mena, S. AU - Ivars, D. AU - Gomez-Cabrera, M. C. PY - 2012 DA - 2012// TI - Epigenetic biomarkers: A new perspective in laboratory diagnostics JO - Clin Chim Acta VL - 413 UR - https://doi.org/10.1016/j.cca.2012.05.021 DO - 10.1016/j.cca.2012.05.021 ID - Garcia-Gimenez2012 ER - TY - JOUR AU - Szyf, M. PY - 2012 DA - 2012// TI - DNA methylation signatures for breast cancer classification and prognosis JO - Genome Med VL - 4 UR - https://doi.org/10.1186/gm325 DO - 10.1186/gm325 ID - Szyf2012 ER - TY - JOUR AU - Duffy, M. J. AU - Napieralski, R. AU - Martens, J. W. AU - Span, P. N. AU - Spyratos, F. AU - Sweep, F. C. PY - 2009 DA - 2009// TI - Methylated genes as new cancer biomarkers JO - Eur J Cancer VL - 45 UR - https://doi.org/10.1016/j.ejca.2008.12.008 DO - 10.1016/j.ejca.2008.12.008 ID - Duffy2009 ER - TY - JOUR AU - Duffy, M. J. PY - 2013 DA - 2013// TI - Tumor markers in clinical practice: a review focusing on common solid cancers JO - Med Princ Pract VL - 22 UR - https://doi.org/10.1159/000338393 DO - 10.1159/000338393 ID - Duffy2013 ER - TY - JOUR AU - Egger, G. AU - Liang, G. AU - Aparicio, A. AU - Jones, P. A. PY - 2004 DA - 2004// TI - Epigenetics in human disease and prospects for epigenetic therapy JO - Nature VL - 429 UR - https://doi.org/10.1038/nature02625 DO - 10.1038/nature02625 ID - Egger2004 ER - TY - JOUR AU - Cai, F. F. AU - Kohler, C. AU - Zhang, B. AU - Wang, M. H. AU - Chen, W. J. AU - Zhong, X. Y. PY - 2011 DA - 2011// TI - Epigenetic therapy for breast cancer JO - Int J Mol Sci VL - 12 UR - https://doi.org/10.3390/ijms12074465 DO - 10.3390/ijms12074465 ID - Cai2011 ER - TY - JOUR AU - Chai, H. AU - Brown, R. E. PY - 2009 DA - 2009// TI - Field effect in cancer-an update JO - Ann Clin Lab Sci VL - 39 ID - Chai2009 ER - TY - JOUR AU - Shen, L. AU - Kondo, Y. AU - Rosner, G. L. AU - Xiao, L. AU - Hernandez, N. S. AU - Vilaythong, J. PY - 2005 DA - 2005// TI - MGMT promoter methylation and field defect in sporadic colorectal cancer JO - J Natl Cancer Inst VL - 97 UR - https://doi.org/10.1093/jnci/dji275 DO - 10.1093/jnci/dji275 ID - Shen2005 ER - TY - JOUR AU - Belshaw, N. J. AU - Elliott, G. O. AU - Foxall, R. J. AU - Dainty, J. R. AU - Pal, N. AU - Coupe, A. PY - 2008 DA - 2008// TI - Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa JO - Br J Cancer VL - 99 UR - https://doi.org/10.1038/sj.bjc.6604432 DO - 10.1038/sj.bjc.6604432 ID - Belshaw2008 ER - TY - JOUR AU - Subramaniam, M. M. AU - Loh, M. AU - Chan, J. Y. AU - Liem, N. AU - Lim, P. L. AU - Peng, Y. W. PY - 2014 DA - 2014// TI - The topography of DNA methylation in the non-neoplastic colonic mucosa surrounding colorectal cancers JO - Mol Carcinogen VL - 53 UR - https://doi.org/10.1002/mc.21951 DO - 10.1002/mc.21951 ID - Subramaniam2014 ER - TY - JOUR AU - Mehrotra, J. AU - Varde, S. AU - Wang, H. AU - Chiu, H. AU - Vargo, J. AU - Gray, K. PY - 2008 DA - 2008// TI - Quantitative, spatial resolution of the epigenetic field effect in prostate cancer JO - Prostate VL - 68 UR - https://doi.org/10.1002/pros.20675 DO - 10.1002/pros.20675 ID - Mehrotra2008 ER - TY - JOUR AU - Yang, B. AU - Bhusari, S. AU - Kueck, J. AU - Weeratunga, P. AU - Wagner, J. AU - Leverson, G. PY - 2013 DA - 2013// TI - Methylation profiling defines an extensive field defect in histologically normal prostate tissues associated with prostate cancer JO - Neoplasia VL - 15 UR - https://doi.org/10.1593/neo.13280 DO - 10.1593/neo.13280 ID - Yang2013 ER - TY - JOUR AU - Dakubo, G. D. AU - Jakupciak, J. P. AU - Birch-Machin, M. A. AU - Parr, R. L. PY - 2007 DA - 2007// TI - Clinical implications and utility of field cancerization JO - Cancer Cell Int VL - 7 UR - https://doi.org/10.1186/1475-2867-7-2 DO - 10.1186/1475-2867-7-2 ID - Dakubo2007 ER - TY - JOUR AU - Yan, P. S. AU - Venkataramu, C. AU - Ibrahim, A. AU - Liu, J. C. AU - Shen, R. Z. AU - Diaz, N. M. PY - 2006 DA - 2006// TI - Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue JO - Clin Cancer Res VL - 12 UR - https://doi.org/10.1158/1078-0432.CCR-06-0467 DO - 10.1158/1078-0432.CCR-06-0467 ID - Yan2006 ER - TY - JOUR AU - Feng, W. AU - Shen, L. AU - Wen, S. AU - Rosen, D. G. AU - Jelinek, J. AU - Hu, X. PY - 2007 DA - 2007// TI - Correlation between CpG methylation profiles and hormone receptor status in breast cancers JO - Breast Cancer Res VL - 9 UR - https://doi.org/10.1186/bcr1762 DO - 10.1186/bcr1762 ID - Feng2007 ER - TY - JOUR AU - Jovanovic, J. AU - Ronneberg, J. A. AU - Tost, J. AU - Kristensen, V. PY - 2010 DA - 2010// TI - The epigenetics of breast cancer JO - Mol Oncol VL - 4 UR - https://doi.org/10.1016/j.molonc.2010.04.002 DO - 10.1016/j.molonc.2010.04.002 ID - Jovanovic2010 ER - TY - JOUR AU - Wojdacz, T. K. AU - Borgbo, T. AU - Hansen, L. L. PY - 2009 DA - 2009// TI - Primer design versus PCR bias in methylation independent PCR amplifications JO - Epigenetics VL - 4 UR - https://doi.org/10.4161/epi.9020 DO - 10.4161/epi.9020 ID - Wojdacz2009 ER - TY - JOUR AU - Tserga, A. AU - Michalopoulos, N. V. AU - Levidou, G. AU - Korkolopoulou, P. AU - Zografos, G. AU - Patsouris, E. PY - 2012 DA - 2012// TI - Association of aberrant DNA methylation with clinicopathological features in breast cancer JO - Oncol Rep VL - 27 ID - Tserga2012 ER - TY - JOUR AU - Avraham, A. AU - Uhlmann, R. AU - Shperber, A. AU - Birnbaum, M. AU - Sandbank, J. AU - Sella, A. PY - 2012 DA - 2012// TI - Serum DNA methylation for monitoring response to neoadjuvant chemotherapy in breast cancer patients JO - Int J Cancer VL - 131 UR - https://doi.org/10.1002/ijc.27526 DO - 10.1002/ijc.27526 ID - Avraham2012 ER - TY - JOUR AU - Migheli, F. AU - Stoccoro, A. AU - Coppedè, F. AU - Wan Omar, W. A. AU - Failli, A. AU - Consolini, R. PY - 2013 DA - 2013// TI - Comparison study of MS-HRM and pyrosequencing techniques for quantification of APC and CDKN2A gene methylation JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0052501 DO - 10.1371/journal.pone.0052501 ID - Migheli2013 ER - TY - STD TI - Office of Pesticide Programs, U.S. Environmental Protection Agency Washington, DC: Assigning values to non-detected/non-quantified pesticide residues in human health food exposure assessments. March 23, 2000. http://www.epa.gov/oppfead1/trac/science/trac3b012.pdf. October 30th 2014. UR - http://www.epa.gov/oppfead1/trac/science/trac3b012.pdf ID - ref27 ER - TY - JOUR AU - Candiloro, I. L. AU - Mikeska, T. AU - Hokland, P. AU - Dobrovic, A. PY - 2008 DA - 2008// TI - Rapid analysis of heterogeneously methylated DNA using digital methylation-sensitive high resolution melting: application to the CDKN2B (p15) gene JO - Epigenetics Chromatin VL - 1 UR - https://doi.org/10.1186/1756-8935-1-7 DO - 10.1186/1756-8935-1-7 ID - Candiloro2008 ER - TY - JOUR AU - Wojdacz, T. K. AU - Moller, T. H. AU - Thestrup, B. B. AU - Kristensen, L. S. AU - Hansen, L. L. PY - 2010 DA - 2010// TI - Limitations and advantages of MS-HRM and bisulfite sequencing for single locus methylation studies JO - Expert Rev Mol Diagn VL - 10 UR - https://doi.org/10.1586/erm.10.46 DO - 10.1586/erm.10.46 ID - Wojdacz2010 ER - TY - JOUR AU - Candiloro, I. L. M. AU - Mikeska, T. AU - Dobrovic, A. PY - 2011 DA - 2011// TI - Assessing combined methylation-sensitive high resolution melting and pyrosequencing for the analysis of heterogeneous DNA methylation JO - Epigenetics VL - 6 UR - https://doi.org/10.4161/epi.6.4.14853 DO - 10.4161/epi.6.4.14853 ID - Candiloro2011 ER - TY - JOUR AU - Kristensen, L. S. AU - Treppendahl, M. B. AU - Asmar, F. AU - Girkov, M. S. AU - Nielsen, H. M. AU - Kjeldsen, T. E. PY - 2013 DA - 2013// TI - Investigation of MGMT and DAPK1 methylation patterns in diffuse large B-cell lymphoma using allelic MSP-pyrosequencing JO - Sci Rep VL - 3 UR - https://doi.org/10.1038/srep02789 DO - 10.1038/srep02789 ID - Kristensen2013 ER - TY - JOUR AU - Wojdacz, T. K. AU - Dobrovic, A. PY - 2007 DA - 2007// TI - Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation JO - Nucleic Acids Res VL - 35 UR - https://doi.org/10.1093/nar/gkm013 DO - 10.1093/nar/gkm013 ID - Wojdacz2007 ER - TY - JOUR AU - Bae, Y. K. AU - Brown, A. AU - Garrett, E. AU - Bornman, D. AU - Fackler, M. J. AU - Sukumar, S. PY - 2004 DA - 2004// TI - Hypermethylation in histologically distinct classes of breast cancer JO - Clin Cancer Res VL - 10 UR - https://doi.org/10.1158/1078-0432.CCR-04-0667 DO - 10.1158/1078-0432.CCR-04-0667 ID - Bae2004 ER - TY - JOUR AU - Shukla, S. AU - Mirza, S. AU - Sharma, G. AU - Parshad, R. AU - Gupta, S. D. AU - Ralhan, R. PY - 2006 DA - 2006// TI - Detection of RASSF1A and RARβ hypermethylation in serum DNA from breast cancer patients JO - Epigenetics VL - 1 UR - https://doi.org/10.4161/epi.1.2.2679 DO - 10.4161/epi.1.2.2679 ID - Shukla2006 ER - TY - JOUR AU - Klajic, J. AU - Fleischer, T. AU - Dejeux, E. AU - Edvardsen, H. AU - Warnberg, F. AU - Bukholm, I. PY - 2013 DA - 2013// TI - Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors JO - BMC Cancer VL - 13 UR - https://doi.org/10.1186/1471-2407-13-456 DO - 10.1186/1471-2407-13-456 ID - Klajic2013 ER - TY - JOUR AU - Yan, P. S. AU - Shi, H. AU - Rahmatpanah, F. AU - Hsiau, T. H. AU - Hsiau, A. H. AU - Leu, Y. W. PY - 2003 DA - 2003// TI - Differential distribution of DNA methylation within the RASSF1A CpG island in breast cancer JO - Cancer Res VL - 63 ID - Yan2003 ER - TY - JOUR AU - Dulaimi, E. AU - Hillinck, J. AU - Ibanez De Caceres, I. AU - Al-Saleem, T. AU - Cairns, P. PY - 2004 DA - 2004// TI - Tumor suppressor gene promoter hypermethylation in serum of breast cancer patients JO - Clin Cancer Res VL - 10 UR - https://doi.org/10.1158/1078-0432.CCR-04-0597 DO - 10.1158/1078-0432.CCR-04-0597 ID - Dulaimi2004 ER - TY - JOUR AU - Lewis, C. M. AU - Cler, L. R. AU - Bu, D. W. AU - Zöchbauer-Müller, S. AU - Milchgrub, S. AU - Naftalis, E. Z. PY - 2005 DA - 2005// TI - Promoter hypermethylation in benign breast epithelium in relation to predicted breast cancer risk JO - Clin Cancer Res VL - 11 ID - Lewis2005 ER - TY - JOUR AU - Krop, I. E. AU - Sgroi, D. AU - Porter, D. A. AU - Lunetta, K. L. AU - LeVangie, R. AU - Seth, P. PY - 2001 DA - 2001// TI - HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells JO - Proc Natl Acad Sci U S A VL - 98 UR - https://doi.org/10.1073/pnas.171138398 DO - 10.1073/pnas.171138398 ID - Krop2001 ER - TY - STD TI - Arai T, Miyoshi Y, Kim SJ, Taguchi T, Tamaki Y, Noguchi S. Association of GSTP1 CpG islands hypermethylation with poor prognosis in human breast cancers. Breast Cancer Res Treat 2006;100:169–76. ID - ref40 ER - TY - JOUR AU - Farzanehfar, M. AU - Vossoughinia, H. AU - Jabini, R. AU - Tavassoli, A. AU - Saadatnia, H. AU - Khorashad, A. K. PY - 2013 DA - 2013// TI - Evaluation of methylation of MGMT (O(6)-methylguanine-DNA methyltransferase) gene promoter in sporadic colorectal cancer JO - DNA Cell Biol VL - 32 UR - https://doi.org/10.1089/dna.2012.1949 DO - 10.1089/dna.2012.1949 ID - Farzanehfar2013 ER - TY - JOUR AU - Supic, G. AU - Kozomara, R. AU - Jovic, N. AU - Zeljic, K. AU - Magic, Z. PY - 2011 DA - 2011// TI - Prognostic significance of tumor-related genes hypermethylation detected in cancer-free surgical margins of oral squamous cell carcinomas JO - Oral Oncol VL - 47 UR - https://doi.org/10.1016/j.oraloncology.2011.05.014 DO - 10.1016/j.oraloncology.2011.05.014 ID - Supic2011 ER - TY - JOUR AU - Krop, I. AU - Maguire, P. AU - Lahti-Domenici, J. AU - Lodeiro, G. AU - Richardson, A. AU - Johannsdottir, H. K. PY - 2003 DA - 2003// TI - Lack of HIN-1 methylation in BRCA1-linked and “BRCA1-like” breast tumors JO - Cancer Res VL - 63 ID - Krop2003 ER - TY - JOUR AU - Gerson, S. L. PY - 2004 DA - 2004// TI - MGMT: its role in cancer aetiology and cancer therapeutics JO - Nat Rev Cancer VL - 4 UR - https://doi.org/10.1038/nrc1319 DO - 10.1038/nrc1319 ID - Gerson2004 ER - TY - JOUR AU - Sunami, E. AU - Shinozaki, M. AU - Sim, M. S. AU - Nguyen, S. L. AU - Vu, A. T. AU - Giuliano, A. E. PY - 2008 DA - 2008// TI - Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors JO - Breast Cancer Res VL - 10 UR - https://doi.org/10.1186/bcr2098 DO - 10.1186/bcr2098 ID - Sunami2008 ER - TY - JOUR AU - Kajabova, V. AU - Smolkova, B. AU - Zmetakova, I. AU - Sebova, K. AU - Krivulcik, T. AU - Bella, V. PY - 2013 DA - 2013// TI - RASSF1A promoter methylation levels positively correlate with estrogen receptor expression in breast cancer patients JO - Transl Oncol VL - 6 UR - https://doi.org/10.1593/tlo.13244 DO - 10.1593/tlo.13244 ID - Kajabova2013 ER -