Skip to main content

Table 1 Patient demographics and relevant clinical characteristics

From: Human breast cancer cells educate macrophages toward the M2 activation status

Factor Entire series CD68a P b CD163a P b HLA-Drαa P b
  ≤369 >369 ≤167.5 >167.5 ≤107 >107
n = 562 n = 277 n = 274 n = 270 n = 267 n = 280 n = 275
Age, years           
≤50 213 95 113   105 98   112 100  
>50 349 182 161 0.093 165 169 0.602 168 175 0.378
Tumor size median           
≤22 mm 283 144 132   137 129   140 138  
>22 mm 278 132 142 0.348 132 138 0.545 139 137 1.000
N.A. 1          
Nodal status           
pN0 65 27 37   28 33   37 28  
pN+ 497 250 237 0.169 242 234 0.468 243 247 0.267
Histological type           
Ductal 399 181 211   171 213   204 192  
Lobular 110 66 43   69 33   47 60  
Other 53 30 20 0.010 30 21 <0.001 29 23 0.274
Histological grade           
Grade 1 46 33 13   26 16   20 25  
Grade 2 264 138 119   153 97   127 132  
Grade 3 250 106 140 0.001 91 152 <0.001 131 118 0.518
N.A. 2          
ER status           
Positive 405 215 181   214 171   191 207  
Negative 157 62 93 0.003 56 96 <0.001 89 68 0.065
HER-2 status           
Positive 170 85 83   72 93   93 77  
Negative 392 192 191 0.920 198 174 0.040 187 198 0.183
Biological group           
ER+, HER-2− 314 165 142   173 123   139 168  
ER+, HER2+ 91 50 39   41 48   52 39  
ER-, HER2+ 79 35 44   31 45   41 38  
ER-, HER2− 78 27 49 0.015 25 51 <0.001 48 30 0.032
Ki67           
≤20 % 271 149 116   158 96   124 140  
>20 % 242 104 134 0.005 92 144 <0.001 126 116 0.252
N.A. 49          
  1. Results are presented as number of patients. aThe cutoff values used correspond to the median values of number of positive cells in the entire series. bChi-square test. ER estrogen receptor, HER-2 human epidermal growth factor receptor 2, N.A. not available