Alcohol consumption, endogenous estrogen and mammographic density among premenopausal women

Breast Cancer Research

Table 4 Above-median percent (>28.5 %) and absolute (>32.4 cm²) mammographic density according to past-year alcohol consumption by type in premenopausal women (n = 202)^a

Alcohol consumption, past year^b		Age-adjusted model^c		Multivariable-adjusted model^d
	Number	Percent density (%)	Absolute density (cm²)	Percent density (%)	Absolute density (cm²)
Total
<1 drink/week	66	1.00	1.00	1.00	1.00
1–6 drinks/week	96	0.90 (0.47, 1.72)	1.10 (0.57, 2.11)	0.92 (0.39, 2.15)	1.16 (0.56, 2.42)
≥7 drinks/week	40	2.37 (1.00, 5.60)	4.38 (1.76, 10.87)	2.78 (0.90. 8.60)	5.08 (1.82, 14.20)
p-trend		0.094	0.004	0.106	0.004
Beer
<2 drinks/week	156	1.00	1.00	1.00	1.00
≥2 drinks/week	45	1.33 (0.66, 2.67)	1.96 (0.97, 3.98)	1.25 (0.51, 3.03)	1.95 (0.90, 4.24)
p-difference		0.423	0.062	0.627	0.092
Wine
<2 drinks/week	169	1.00	1.00	1.00	1.00
≥2 drinks/week	33	2.18 (0.97, 4.93)	2.60 (1.14, 5.93)	2.06 (0.77, 5.53)	2.47 (1.03, 5.92)
p-difference		0.060	0.024	0.152	0.043
Others^e
<2 drinks/week	184	1.00	1.00	1.00	1.00
≥2 drinks/week	18	2.80 (0.85, 9.17)	2.86 (0.88, 9.35)	2.55 (0.67, 9.64)	2.65 (0.79, 9.04)
p-difference		0.090	0.081	0.196	0.119

Data presented as odds ratio (95 % confidence interval). All analyses used multivariable logistic regression models
FFQ food frequency questionnaire
^aNumbers may vary owing to missing information
^bAlcohol consumption reported in past year, FFQ. One drink or unit is equal to 10 g alcohol
^cAdjusted for age (continuous)
^dAdjusted for age (continuous), body mass index (continuous), number of children (continuous), previous oral contraceptives (categorical), and current smokers (categorical)
^eIncludes spirits and fortified wine

ISSN: 1465-542X