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Fig. 1 | Breast Cancer Research

Fig. 1

From: The molecular landscape of premenopausal breast cancer

Fig. 1

Differences in outcome and gene expression comparing premenopausal (preM) and postmenopausal (postM) tumors. a Principal component analysis (PCA) using RNA seq data from The Cancer Genome Atlas (TCGA). Tumor: purple triangle, estrogen receptor-negative (ER–)/preM; red diamond, ER–/postM; orange star, estrogen receptor-positive (ER+)/preM; pink square, ER+/postM. Normal: light blue triangle, ER–/preM; black diamond, ER–/postM; green star, ER+/preM; dark blue square, ER+/postM. b Heatmap showing genes differentially expressed (n = 1,609) between ER+/preM and. ER+/postM, using RNA-Seq data. Each gene is normalized to standard normal distribution with green indicating lower expression, and red indicating higher expression. PC principal component

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