Table 3 Parameter estimates of tumour growth, time to symptomatic detection, and screening sensitivity
Model for tumour growth: | ||
Parameter | Point estimate | Confidence interval (profile likelihood) |
Intercept, α 1 | −0.65 | (−0.99, −0.28) |
Body mass index coefficient, α 2 | −0.02 | (−0.05, 0.00) |
Coefficient of variation, σ 2 | 0.40 | (0.31, 0.52) |
Model for screening sensitivity: | ||
Parameter | Point estimate | Confidence interval (profile likelihood) |
Intercept, β 1 | −4.68 | (−5.10, −4.30) |
Tumour size coefficient, β 2 | 0.57 | (0.49, 0.66) |
Percentage mammographic density coefficient, β 3 | −2.39 | (−3.81, −1.01) |
Model for time to symptomatic detection: | ||
Parameter | Point estimate | Confidence interval (profile likelihood) |
Intercept, η 1 | −8.26 | (−8.82, −7.88) |
Total breast area coefficient, η 2 | −0.17 | (−0.32, −0.04) |