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Table 2 Information on rearrangement and copy number variation

From: Contralateral breast cancer can represent a metastatic spread of the first primary tumor: determination of clonal relationship between contralateral breast cancers using next-generation whole genome sequencing

Patient

Tumor

Shared rearrangements

Total rearrangements

Fraction of rearrangements (%)

Combined shared fraction of rearrangements (%)

Fraction of shared aberrant copy number events (%)

1

BC1

7

15

47

15

18

 

BC2

7

40

18

  

2

BC1

53

64

83

39

15

 

BC2

53

124

43

  

3

BC1

28

151

19

9

10

 

BC2

28

203

14

  

4

BC1

17

256

7

6

18

 

BC2

17

75

23

  

5

BC1

27

67

40

13

20

 

BC2

27

170

16

  

6

BC1

62

86

72

46

23

 

BC2

62

111

56

  

7

BC1

33

128

26

12

22

 

BC2

33

173

19

  

8

BC1

68

87

78

76

28

 

BC2

68

71

96

  

9

BC1

20

84

24

10

25

 

BC2

20

128

16

  

10

BC1

6

58

10

7

28

 

BC2

6

30

20

  

Summary

      

Paired tumors

Median

28

87

24

13

21

 

Minimum

6

15

7

6

10

 

Maximum

68

256

96

76

28

Random pairs

Median

4

75

4

2

13

 

Minimum

0

6

0

0

6

 

Maximum

25

254

43

18

22

  1. BC1 first breast cancer, BC2 second breast cancer
  2. Summarized numbers for randomized matching