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Fig. 2 | Breast Cancer Research

Fig. 2

From: Mammographic density and breast cancer in women from high risk families

Fig. 2

Association between mammographic density (MD) and subsequent breast cancer (BC) among BRCA1 or BRCA2 mutation carriers: analysis stratified by other explanatory variables. Odds ratios (OR) and 95 % CI correspond to an increase in one category of MD. Estimators adjusted for age at mammogram, menopausal status, body mass index (BMI), parity, age at first live birth, use of hormonal replacement therapy (HRT), type of image and time elapsed from mammogram to either breast cancer diagnosis (cases) or end of follow up (non-cases). P value reflects the statistical significance of the interaction term between MD and the corresponding variable in all cases except for BC subtype, for which the P value is for the test of heterogeneity of the MD effect according to the type of tumor. HPT hormone preventative treatment, ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2

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