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Table 2 Association of symptom cluster (arthralgia, fatigue, and insomnia) with inflammatory biomarkers

From: Arthralgia among women taking aromatase inhibitors: is there a shared inflammatory mechanism with co-morbid fatigue and insomnia?

 

Univariate analysis

Multivariate analysis

 

Coefficient (95 % CI)

p value

Coefficient (95 % CI)

p value

CRP

117.3 (49.3–185.3)

0.001

93.1 (25.1–161.1)

0.008

Eotaxin

87.3 (40.8–133.7)

<0.001

79.9 (32.5–127.2)

0.001

MCP-1

178 (63–293.2)

0.003

151.2 (32.7–269.8)

0.013

VDBP

21,530.8 (8088.4–34,973.2)

0.002

19,422 (5500.5–33,344)

0.006

  1. Data shown are results of multivariate linear regression analyses controlled for race, body mass index, chemotherapy status, non-steroidal anti-inflammatory drug use, and age
  2. CI confidence interval, CRP C-reactive protein, MCP-1 monocyte chemoattractant protein 1, VDBP vitamin D–binding protein
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Breast Cancer Research

ISSN: 1465-542X

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