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Table 2 Association of symptom cluster (arthralgia, fatigue, and insomnia) with inflammatory biomarkers

From: Arthralgia among women taking aromatase inhibitors: is there a shared inflammatory mechanism with co-morbid fatigue and insomnia?

  Univariate analysis Multivariate analysis
  Coefficient (95 % CI) p value Coefficient (95 % CI) p value
CRP 117.3 (49.3–185.3) 0.001 93.1 (25.1–161.1) 0.008
Eotaxin 87.3 (40.8–133.7) <0.001 79.9 (32.5–127.2) 0.001
MCP-1 178 (63–293.2) 0.003 151.2 (32.7–269.8) 0.013
VDBP 21,530.8 (8088.4–34,973.2) 0.002 19,422 (5500.5–33,344) 0.006
  1. Data shown are results of multivariate linear regression analyses controlled for race, body mass index, chemotherapy status, non-steroidal anti-inflammatory drug use, and age
  2. CI confidence interval, CRP C-reactive protein, MCP-1 monocyte chemoattractant protein 1, VDBP vitamin D–binding protein