Table 3 Performance of risk models assessed in at least two models
From: Can the breast screening appointment be used to provide risk assessment and prevention advice?
Risk model performance (country) | Gail | Claus | BRCAPRO Ford | Tyrer-Cuzick | BOADICEA |
|---|---|---|---|---|---|
Quante et al. [42] (USA) | 0.632 (0.576-689) | Not assessed | Not assessed | 0.695 (0.638- 0.752) | Not assessed |
Powell et al. [41] (USA) | 0.62 (0.59-0.66) | Not assessed | 0.60 (0.56-0.63) | 0.65 (0.61-0.68) | Not assessed |
Performance in general population | Well validated but needs more precision in familial setting | Not useful | Not useful | Has been validated and outperforms Gail | May be useful but requires addition of non-genetic factors |