Fig. 1

Copy number alterations of specific genes associated with ductal carcinoma in situ (DCIS) phenotype and disease stage. *Small DCIS lesions are defined as less than 15 mm, and large DCIS lesions are defined as more than 40 mm. aCGH, array-comparative genomic hybridization; CGH, comparative genomic hybridization; ER, estrogen receptor; FISH, fluorescence in situ hybridisation; HG, high grade; MLPA, multiplex ligation-dependent probe amplification; non-HG, non-high grade; PCR, polymerase chain reaction