Table 2 Univariate comparison of demographic and tumor-related characteristics between pCR and non-pCR patients
Characteristic | Patients with pCR, number (%) or median (IQR) | Patients with non-pCR, number (%) or median (IQR) | P value |
|---|---|---|---|
Overall population | 16 (40) | 24 (60) | -- |
Age (years), median | 45.5 (35.5–51.5) | 49.5 (34.3–53.0) | 0.97 |
BMI (kg/m2), median | 25.7 (23.3–29.6) | 27.3 (24.2–31.0) | 0.49 |
Race | 0.63 | ||
White | 15 (93.8) | 20 (83.3) | |
Black/Asian/Hispanic | 1 (6.2) | 4 (16.7) | |
Charlson comorbidity index | 0.75 | ||
<2 (mild) | 7 (43.8) | 9 (37.5) | |
≥2 (moderate–high) | 9 (56.2) | 15 (62.5) | |
Menopausal status | 1.00 | ||
Premenopausal | 9 (56.2) | 14 (58.3) | |
Postmenopausal | 7 (43.8) | 10 (41.7) | |
AJCC clinical stageb | 0.12 | ||
II | 11 (68.8) | 10 (41.7) | |
III | 5 (31.2) | 14 (58.3) | |
ER/PR statusb | 0.02 | ||
Positive | 5 (31.2) | 17 (70.8) | |
Negative | 11 (68.8) | 7 (29.2) | |
Lymphovascular invasion | 0.21 | ||
Absent | 15 (93.8) | 18 (75.0) | |
Present | 1 (6.2) | 6 (25.0) | |
Nuclear grade | 0.33 | ||
Grade 1/2 | 4 (25.0) | 10 (41.7) | |
Grade 3 | 12 (75.0) | 14 (58.3) | |
Neoadjuvant regimen | 1.00 | ||
AC/TH | 13 (81.3) | 20 (83.3) | |
Othera | 3 (18.7) | 4 (16.7) | |
Operative approachb | 0.09 | ||
BCS + XRT | 8 (50.0) | 5 (20.8) | |
Mastectomy ± XRT | 8 (50.0) | 19 (79.2) |