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Table 3 Changes in density measures over menopause in weight change groups (n = 591)

From: The effect of weight change on changes in breast density measures over menopause in a breast cancer screening cohort

  Weight loss, more than −3.0 % Stable weight, −3.0 %; +3.0 % Weight gain, more than +3.0 % P-trend
Number of women, n (%) 109 (18.5) 255 (43.1) 227 (38.4)  
Δ Breast density (%), mean (95 % CI) −5.0 (−8.0; −2.1) −6.8 (−9.0; −4.5) −10.2 (−12.5; −7.9) 0.001
Δ Dense area (cm2), mean (95 % CI) −16.7 (−20.1; −13.4) −16.4 (−18.9; −13.9) −18.1 (−20.6; −15.5) 0.437
Δ Nondense area (cm2), mean (95 % CI) −6.1 (−11.9; −0.4) −0.6 (−4.9; 3.8) 5.3 (0.9; 9.8) <0.001
  1. Means and 95 % confidence intervals (CIs) were adjusted for age, body mass index, and waist circumference at baseline, parity, age at first childbirth, time between pre- and post-menopausal mammogram, age at menarche, and the pre-menopausal breast measure of interest (premenopausal percentage breast density, dense area, or nondense area)