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Table 3 Changes in density measures over menopause in weight change groups (n = 591)

From: The effect of weight change on changes in breast density measures over menopause in a breast cancer screening cohort

 

Weight loss, more than −3.0 %

Stable weight, −3.0 %; +3.0 %

Weight gain, more than +3.0 %

P-trend

Number of women, n (%)

109 (18.5)

255 (43.1)

227 (38.4)

 

Δ Breast density (%), mean (95 % CI)

−5.0 (−8.0; −2.1)

−6.8 (−9.0; −4.5)

−10.2 (−12.5; −7.9)

0.001

Δ Dense area (cm2), mean (95 % CI)

−16.7 (−20.1; −13.4)

−16.4 (−18.9; −13.9)

−18.1 (−20.6; −15.5)

0.437

Δ Nondense area (cm2), mean (95 % CI)

−6.1 (−11.9; −0.4)

−0.6 (−4.9; 3.8)

5.3 (0.9; 9.8)

<0.001

  1. Means and 95 % confidence intervals (CIs) were adjusted for age, body mass index, and waist circumference at baseline, parity, age at first childbirth, time between pre- and post-menopausal mammogram, age at menarche, and the pre-menopausal breast measure of interest (premenopausal percentage breast density, dense area, or nondense area)