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Table 2 Mechanisms of E-cadherin loss

From: Molecular drivers of lobular carcinoma in situ

Reference Mechanism Sample size Percentage E-cadherin loss
Vos et al. 1997 [97] LOH 7 86 %
Palacios et al. 2003 [98] LOH 7 100 %
Sarrió et al. 2003 [99] LOH 9 100 %
Mastracci et al. 2005 [100] LOH 13 15 %
Vos et al. 1997 [97] Mutation 2 100 %
Rieger-Christ et al. 2001 [101] Mutation 21 38 %
Sarrió et al. 2003 [99] Mutation 3 100 %
Mastracci et al. 2005 [100] Mutation 14 100 %
Sarrió et al. 2003 [99] Methylation 9 11 %
Morrogh et al. 2012 [77] Transcription 36 100 %
  1. LOH loss of heterozygosity