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Table 2 Correlation between CD34-stained mean vessel areas (MVA) and DOT parameters

From: Macroscopic optical physiological parameters correlate with microscopic proliferation and vessel area breast cancer signatures

Analysis of corrlelation with MVA (μm2) rStO2 rTHC rHbO2 rHb s
Pearson’s correlation coefficient 0.26 0.51 0.48 −0.10 0.32
P-value 0.291 0.027 0.038 0.684 0.182
Spearman’s correlation coefficient 0.45 0.67 0.63 −0.22 0.52
P-value 0.057 0.002 0.005 0.362 0.024
  1. MVA was correlated with relative total hemoglobin concentration (rTHC), relative oxyhemoglobin concentration (rHbO2) and relative reduced-scattering coefficients (rμs’) (n = 19). Results with statistical significance (p-value <0.05) are shown in bold. DOT denotes diffuse optical tomography, rStO2 denotes relative tissue oxygen saturation, and rHb denotes relative deoxyhemoglobin concentration