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Fig. 5 | Breast Cancer Research

Fig. 5

From: Quantitative assessment of background parenchymal enhancement in breast MRI predicts response to risk-reducing salpingo-oophorectomy: preliminary evaluation in a cohort of BRCA1/2 mutation carriers

Fig. 5

Representative examples of fibroglandular tissue (FGT) and background parenchymal enhancement (BPE) from a magnetic resonance imaging (MRI) slice obtained pre-RRSO and post-RRSO in a woman who developed breast cancer after undergoing risk-reducing salpingo-oophorectomy (RRSO). FGT is circumscribed by green contours. BPE is estimated in both the first and third subtraction series (SUB 1 and SUB 3, respectively). This 36-year-old (at time of RRSO) woman had her pre-RRSO MRI at 1 month before RRSO and her post-RRSO MRI at 6 months after RRSO. Breast cancer (ductal carcinoma in situ) was diagnosed in her right breast 6 years after RRSO, and her final pathologic examination showed in situ carcinoma with 2 foci of microinvasion (<0.1 cm). This example shows no decrease of BPE and FGT after RRSO. The volumetric pre-RRSO BPE % values were 10.7 % (SUB 1) and 10.6 % (SUB 3) and after RRSO, and BPE % values were 7.1 % (SUB 1) and 8.5 % (SUB 3)

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