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Fig. 1 | Breast Cancer Research

Fig. 1

From: Quantitative assessment of background parenchymal enhancement in breast MRI predicts response to risk-reducing salpingo-oophorectomy: preliminary evaluation in a cohort of BRCA1/2 mutation carriers

Fig. 1

Illustration of our fully automated computer algorithm for quantifying magnetic resonance imaging (MRI) background parenchymal enhancement (BPE) and fibroglandular tissue (FGT). Representative 2D and 3D tissue segmentations in selected breast MRI scans are shown. a A breast MRI slice of the T1-weighted sequence. b Segmentation of the whole breast (red contour) and FGT (green contour). c 3D display of FGT (green) relative to the whole breast (red). d This dynamic contrast-enhanced MRI subtraction (SUB) image corresponds to the T1 slice shown in (a). e BPE (purple contour) estimated over the FGT area in the SUB image. f 3D display of BPE (purple), FGT (green), and whole breast (red)

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