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Figure 3 | Breast Cancer Research

Figure 3

From: Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery

Figure 3

High heating potential of magnetic nanoparticles (MNP) in conjunction with moderate hydrodynamic size and negative ζ-potential. Specific absorption rate (SAR) and intrinsic loss power (ILP) values of MF66-N6L, MF66-DOX, MF66-N6LDOX and the non-functionalized variant MF66 after suspension in different media (water, 1% (w/v) agar in water, 10% PVA in dimethyl sulfoxide (DMSO)/water (80/20% (v/v)). a Immersion in agar and PVA mimics different degrees of MNP immobilization, as it occurs after uptake in tumor tissue. Values of hydrodynamic size (z-average) (b) and ζ-potential (c) are also displayed for the three functionalized MNP formulations and for the non-functionalized variant.

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