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Figure 11 | Breast Cancer Research

Figure 11

From: Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery

Figure 11

Histological staining for the proliferation marker Ki67, anti-apoptotic protein Bcl2 and tumor vascularization by CD31. Immunohistochemistry of paraffin-embedded formaldehyde-fixed tumor tissue sections stained for expression of Ki67 (red), Bcl2 (red) and CD31 (brown) antigens for animals treated with MF66-Nucant multivalent pseudopeptide (MF66-N6L), MF66-doxorubicin (MF66-DOX) or MF66-N6LDOX with or without alternating magnetic field (AMF) exposure as well as the ddH2O controls (Control) without AMF treatment. One representative image for each group is shown. Scale bar = 100 μm.

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