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Figure 2 | Breast Cancer Research

Figure 2

From: Adipose cells promote resistance of breast cancer cells to trastuzumab-mediated antibody-dependent cellular cytotoxicity

Figure 2

Adipocyte- and preadipocyte-derived soluble factors inhibit antibody-dependent cellular cytotoxicity. (A) Antibody-dependent cellular cytotoxicity (ADCC) assays on BT-474 cells performed in the presence of the conditioned media from differentiated human multipotent adipose-derived stem cells (#hMADS-CM) or human multipotent adipose-derived stem cells (hMADS-CM) cells (vol/vol = 1/1). (B) Similar to (A), but the CM were from adipose-derived stem cells (ASC-CM) or in vitro differentiated #ASCs (#ASC-CM) obtained from abdominal adipose tissue. Data represent the means ± SD of three independent experiments, each performed in triplicate. *P < 0.05; **P < 0.01.

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