Skip to main content

Table 2 Overall classification, estrogen receptor (ER)-positive classification, ER-negative classification and classification using the MammaPrint profile

From: Long non-coding RNA expression profiles predict metastasis in lymph node-negative breast cancer independently of traditional prognostic markers

Profile Number of samples (metastasis/non-metastasis) Sensitivity (true positive) Specificity (true negative) Accuracy a P b
LncRNA classification
Overall classification 82/82 90 (74) 65 (53) 77 7.3e-14
ER-positive classification 55/55 91 (50) 64 (35) 77 1.1e-9
ER-negative classification 17/17 94 (16) 0 (0) 47 0.50
MammaPrint classification      
All samples 82/82 90 (74) 22 (18) 56 0.03
ER-positive samples 55/55 91 (50) 55 (30) 73 1.9e-7
ER-negative samples 17/17 94 (16) 0 (0) 47 0.50
  1. aMean of sensitivity and specificity. bFisher’s exact test, one-tailed. Classification performances were assessed by leave one pair out cross-validation with a threshold that resulted in ≥90% sensitivity and maximized the specificity.