Table 2 Functional annotation of fuzzy clusters by means of immunohistochemistry
Marker interpretation | C1 | C2 | C3 | P -value |
|---|---|---|---|---|
( n = 24) | ( n = 48) | ( n = 35) | ||
CK5/6 and/or HER1 positive | 50% | 71% | 0.077 | |
CK5 and/or HER1 positive | 50% | 92% | <10−5 | |
Ki-67 positive | 29% | 87% | 2.10−7 | |
AR positive | 73% | 5% | <10−9 | |
FOXA1 positive | 73% | 5% | 7.10−13 | |
E-cadherin positive | 64% | 48% | 0.197 | |
- | 42% | 56% | 0.236 | |
Claudin 3 positive | 38% | 59% | 0.085 | |
- | 58% | 60% | 0.879 | |
Claudin 4 positive | 91% | 93% | 0.672 | |
- | 92% | 94% | 0.990 | |
Claudin 7 positive | 18% | 12% | 0.485 | |
- | 12% | 11% | 0.990 | |
Claudin 3, 4, 7 negative and/or E-cadherin negative | 38% | 52% | 0.261 | |
- | 58% | 43% | 0.163 | |