Figure 6

Phospho-epidermal growth factor receptor (p-EGFR) tumor and stromal staining intensity is correlated in inflammatory breast cancer (IBC) but not in non-IBC. Primary tumor samples obtained from breast cancer patients at MD Anderson Cancer Center (details about the patients are described in reference [18]) were used to create a tissue microarray (TMA), which was stained for p-EGFR. Tumor and stroma staining was scored by a pathologist specialized in IBC. (A) Representative p-EGFR staining of tumor section from IBC patient (estrogen receptor (ER)/progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) negative) scored as tumor 3+ and stroma 3+. (B) Representative p-EGFR staining of tumor section from non-IBC patient (ER/PR negative and HER2 positive) scored as tumor 2+ and stroma 0 to 1. 400X magnification in both images.