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Figure 3 | Breast Cancer Research

Figure 3

From: Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF

Figure 3

Overall survival in breast cancer patients stratified by tissue factor pathway inhibitor (TFPI) and tissue factor (TF) expression in tumors. Kaplan-Meier survival curve with overall survival (OS) with 10-year censoring as endpoint, stratified according to high (above the median) and low (below median) total TFPI (α + β) gene expression levels (A), TFPIαa gene expression levels (B), TFPIβ gene expression levels (C), and TF gene expression levels (D), in all tumors and selected clinical subgroups in which survival data were available. Analyses were performed using the Gene expression based Outcome for Breast cancer Online (GOBO) database, and the log-rank test was used to calculate P-values. aFor TFPIα expression results were obtained by merging the two available probe sets, as specified in Additional file 4: Table S3.

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