c-Met expression in basal-like breast cancer. Characteristic features of basal-like breast cancer (images are from the same tumour). (A) Circumscribed tumour front (arrowheads) and associated chronic inflammatory cell infiltrate (arrow). (B) Tumour fibrosis. (C) High-grade cytology, with nuclear enlargement and pleomorphism (arrowheads), along with prominent mitotic figures (arrows). Haematoxylin and eosin; (A) and (B) × 10 objective, (C) × 40 objective. Scale bars represent 20 μm. (D) High cytoplasmic and membranous (arrowheads) expression of c-Met. Immunohistochemistry, ×40 objective. Scale bar represents 20 μm. Inset image is at 200% magnification.