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Table 2 Main baseline characteristics of the study population according to quartiles of estimated dietary dioxin exposure, E3N cohort, 1993 (n = 63,830)

From: Estimated dietary dioxin exposure and breast cancer risk among women from the French E3N prospective cohort

  Dietary dioxin exposure (pg/kg body weight/day)
  <0.98 [0.98, 1.23] [1.23, 1.52] ≥1.52
Age (years), mean ± SD 53.5 ± 6.8 53.0 ± 6.7 52.5 ± 6.5 51.9 ± 6.3
Energy intake (kcal/day), mean ± SD 1710.3 ± 391.7 2003.6 ± 405.5 2231.6 ± 437.0 2580.8 ± 513.4
Smoking status, n (%)     
 Non-smoker 8672 (54.3) 8611 (54.0) 8614 (54.0) 8429 (52.8)
 Former smoker 5102 (32.0) 5259 (33.0) 5243 (32.9) 5288 (33.1)
 Smoker 2184 (13.7) 2087 (13.1) 2101 (13.2) 2240 (14.0)
Combined menopausal status, MHT a use and BMI b , n (%)     
 Premenopausal     
 BMI <25 kg/m2 4797 (73.7) 5665 (82.2) 6362 (87.1) 7143 (91.5)
 BMI ≥25 kg/m2 1715 (26.3) 1227 (17.8) 942 (12.9) 667 (8.5)
 Postmenopausal not using MHT     
 BMI <25 kg/m2 2572 (58.7) 2679 (70.4) 2715 (76.5) 2692 (82.8)
 BMI ≥25 kg/m2 1813 (41.4) 1129 (29.7) 833 (23.5) 560 (17.2)
 Postmenopausal using MHT     
 BMI <25 kg/m2 3526 (69.7) 4127 (78.5) 7261 (83.5) 4344 (88.7)
 BMI ≥25 kg/m2 1535 (30.3) 1130 (21.5) 845 (16.6) 551 (11.3)
Parity and age at first birth, n (%)     
 No child 2035 (12.8) 1890 (11.8) 1793 (11.2) 1685 (10.6)
 ≤2 children <30 years old 7661 (48.0) 7913 (49.6) 8076 (50.6) 8393 (52.6)
 ≤2 children ≥30 years old 1527 (9.6) 1402 (8.8) 1464 (9.2) 1378 (8.6)
 ≥3 children 4735 (29.7) 4752 (29.8) 4625 (29.0) 4501 (28.2)
Breastfeeding, n (%)     
 Ever 8916 (55.9) 9234 (55.9) 9321 (58.4) 9365 (58.7)
 Never 7042 (44.1) 6723 (42.1) 6637 (41.6) 6592 (41.3)
Alcohol intake, n (%)     
 0 g/day 2636 (16.5) 2021 (12.7) 1685 (10.6) 1356 (8.5)
 <6.9 g/day 6688 (41.9) 6354 (39.8) 5897 (37.0) 5181 (32.5)
 ≥6.9 g/day 6634 (41.6) 7582 (47.5) 8376 (52.5) 9420 (59.0)
Personal history of benign breast disease, n (%)     
 Yes 4292 (26.9) 4570 (28.6) 4907 (30.8) 4949 (31.0)
 No 11666 (73.1) 11387 (71.4) 11051 (69.3) 11008 (69.0)
  1. aMHT, menopausal hormone treatment; bBMI, body mass index.