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Table 6 MicroRNA signatures for estrogen receptor, progesterone receptor, and HER2/neu receptor status in breast cancer

From: Dysregulation of microRNAs in breast cancer and their potential role as prognostic and predictive biomarkers in patient management

miRNA Median accuracy, percentage Increased miRNA expression gives higher probability of:
ER status   
miR-342 83.3 ER (+) status
miR-299-3p 100 ER (−) status
miR-217 100 ER (+) status
miR-190 100 ER (−) status
miR-135b 100 ER (-) status
miR-218 100 ER (+) status
PR status   
miR-520 g 83.3 PR (−) status
miR-377 83.3 PR (+) status
miR-527-518a 100 PR (−) status
miR-520f-520c 100 PR (+) status
HER2/neu status   
miR-520d 100 HER2/neu (+) status
miR-181c 100 HER2/neu (−) status
miR-302c 100 Weak response
miR-376b 100 HER2/neu (+) status
miR-30e-3p 100 Weak response
  1. Lowery et al. [72] (2009). ER, estrogen receptor; miRNA, microRNA; PR, progesterone receptor.