Dysregulation of microRNAs in breast cancer and their potential role as prognostic and predictive biomarkers in patient management

Table 3 The most prominent microRNA detection methods

Detection method	Throughput	Sensitivity	Specificity	Reference
Northern blotting	Low	Low	High	[53]
Microarray	High	Low	Low	[54]
Bead-based flow cytometry	High	Medium	High	[6]
qRT-PCR	High	High	High	[55]
In situ hybridization	Low	Low	Low	[56]
Next-generation sequencing	High	High	High	[57,58]

ISSN: 1465-542X