Benefit and harm with screening mammography and use of aspirin over 10 years
. Shown are the 10-year risk of death from breast cancer (bars above 0) and the 10-year risk of the diagnosis of breast cancer (bars below 0) among women aged 40 years and 50 years, with and without mammography screening. Also shown are the 10-year risk of death from cancer (bar above 0) and the 10-year risk of major extracranial bleeding, defined as bleeding necessitating transfusion or resulting in death (bar below 0), associated with the use or non-use of aspirin as a primary preventive measure (on the basis of findings from randomized trials). In each pair (no screening versus screening and no aspirin versus aspirin), the difference between the percentages represented by the bars shows the absolute benefit or harm associated with screening mammography or the use of aspirin. Background data are derived from the literature.