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Table 2 mRNA expression levels in nontransformed and malignant breast cells a

From: Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy

Cell line

CDK11 b

CK2α

CK2α ′

MCF-10A

1.53 ± 0.04

2.90 ± 0.35

5.19 ± 0.36

MCF-12A

1.38 ± 0.07

1.91 ± 0.17

1.05 ± 0.03

MDA-MB-231

0.96 ± 0.10

2.91 ± 0.48

0.40 ± 0.004

MDA-MB-468

0.87 ± 0.11

3.18 ± 0.06

2.91 ± 0.39

SUM-149

0.31 ± 0.001

0.66 ± 0.08

1.84 ± 0.01

  1. Data presented as mean ± standard error. amRNA expression normalized to HPRT-1. bBoth human genes (CDC2L1 and CDC2L2) recognized by PCR probes.
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Breast Cancer Research

ISSN: 1465-542X

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