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Table 1 Characteristics of breast cancer cell lines

From: Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy

Cell line a

Transformed

Molecular subtype

Histological pathology b

ER expressed

PR expressed

Her2 amplified

MCF-10A

No

Basal

Fibrocystic

No

No

No

MCF-12A

No

Basal

Fibrocystic

No

No

No

BT-474

Yes

Luminal B

DC

Yes

Yes

Yes

MCF-7

Yes

Luminal A

AC

Yes

Yes

No

MCF-7LTamR

Yes

Luminal A

AC

Yes

Yes

No

MDA-MB-231

Yes

Basal

AC

No

No

No

MDA-MB-468

Yes

Basal

AC

No

No

No

SUM-149

Yes

Basal

IBC

No

No

No

SUM-190

Yes

Basal

IBC

No

No

Yes

  1. AC, adenocarcinoma; DC, ductal carcinoma; ER, estrogen receptor; IBC, inflammatory breast cancer; PR, progesterone receptor; Her2, human epidermal growth factor receptor 2. aMCF-10A and MCF-12A are spontaneously immortalized cells. bOriginal tissue or tumor.