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Table 4 Gene profile of BC PDX primary tumors associated with CTC clusters and LM

From: Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis

Genes Average fold change in lines with CTC clusters versus no CTC clusters Average fold change in lines with LM versus no LM
HLA-DP1A* 0.05 0.02
GJA1* 0.04 0.03
PEG3^ 42.42 25.63
XIST^ 17.03 43.5
  1. *Downregulated genes; ^Upregulated genes.
  2. BC, breast cancer; CTC, circulating tumor cell; LM, lung metastasis; PDX, patient-derived xenograft.