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Table 4 Gene profile of BC PDX primary tumors associated with CTC clusters and LM

From: Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis

Genes

Average fold change in lines with CTC clusters versus no CTC clusters

Average fold change in lines with LM versus no LM

HLA-DP1A*

0.05

0.02

GJA1*

0.04

0.03

PEG3^

42.42

25.63

XIST^

17.03

43.5

  1. *Downregulated genes; ^Upregulated genes.
  2. BC, breast cancer; CTC, circulating tumor cell; LM, lung metastasis; PDX, patient-derived xenograft.
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Breast Cancer Research

ISSN: 1465-542X

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