|
PDX line
|
CTC detection rate (%)
|
Number of CTCs per 20 K nucleated cells (≈20 μl of blood)
|
BM-DTC detection rate (%)
|
Number of BM-DTCs per 2 × 10
6
BM cells
|
LM rate [26] (%)
|
|---|
|
BCM-3107*
|
1/4 (25)
|
7
|
1/2 (50)
|
1
|
0
|
|
BCM-3143
|
0/2 (0)
|
0
|
0/2 (0)
|
0
|
0
|
|
BCM-3204*
|
2/4 (50)Cl
|
3-43
|
0/2 (0)
|
0
|
29
|
|
BCM-3561*
|
2/4 (50)
|
1
|
ND
|
ND
|
0
|
|
BCM-3613*
|
1/3 (33)
|
7
|
0/2 (0)
|
0
|
24
|
|
BCM-3807
|
0/4 (0)
|
0
|
1/2 (50)
|
29
|
0
|
|
BCM-3887*
|
3/4 (75)Cl
|
3-92
|
1/5 (20)
|
<1
|
14
|
|
BCM-3963*
|
1/6 (17)
|
7
|
0/4 (0)
|
0
|
14
|
|
BCM-4195
|
0/2 (0)
|
0
|
0/2 (0)
|
0
|
0
|
|
BCM-4272*
|
3/3 (100)
|
<1-25
|
4/6 (67)Cl
|
<1-132
|
29
|
|
BCM-4664*
|
1/3 (33)
|
2
|
ND
|
ND
|
0
|
|
BCM-4888*
|
5/5 (100)Cl
|
3-28
|
0/4 (0)
|
0
|
67
|
|
BCM-5097
|
3/6 (50)Cl
|
10-91
|
3/5 (60)
|
12-30
|
36
|
|
BCM-5156
|
3/5 (60)
|
1-28
|
1/2 (50)
|
2
|
0
|
|
BCM-5438
|
2/2 (100)
|
2-3
|
2/2 (100)
|
4-67
|
0
|
|
BCM-5471
|
3/6 (50)Cl
|
1-10
|
2/4 (50)Cl
|
<1-6
|
33
|
|
BCM-5998
|
5/7 (71)
|
<1-27
|
6/8 (75)Cl
|
1-40
|
0
|
|
BCM-6257
|
3/3 (100)Cl
|
3-4
|
2/3 (67)Cl
|
22-39
|
6
|
- BC, breast cancer; BM, bone marrow; BM-DTCs, disseminated tumor cells in bone marrow; CTC,s circulating tumor cells, LM, lung metastasis, ND, not determined, PDX, patient-derived xenograft. Cl represents presence of CTCs and BM-DTCs in clusters. * indicates the lines with published Affymetrix data.
