Table 1 Baseline characteristics according to maximum standardized uptake values a
Characteristics | All patients | High SUV | Low SUV | P -value b | |
|---|---|---|---|---|---|
Age at diagnosis, yr | 0.698 | ||||
Median (range) | 48 (25 to 80) | 48 (25 to 79) | 49 (28 to 80) | ||
Histology | <0.001 | ||||
Invasive ductal carcinoma | 416 (83.9) | 173 (87.8) | 243 (81.3) | ||
Invasive lobular carcinoma | 22 (4.4) | 1 (0.5) | 21 (7.0) | ||
Mucinous carcinoma | 13 (2.6) | 2 (1.0) | 11 (3.7) | ||
Tubular carcinoma | 6 (1.2) | 0 (0.0) | 6 (2.0) | ||
Medullary carcinoma | 4 (0.8) | 4 (0.8) | 0 (0.0) | ||
Other invasive carcinoma | 35 (7.7) | 17 (8.6) | 18 (6.0) | ||
T classification | <0.001 | ||||
T1 | 270 (54.4) | 68 (34.5) | 202 (67.6) | ||
T2 | 217 (43.8) | 126 (64.0) | 91 (30.4) | ||
T3 | 9 (1.8) | 3 (1.5) | 6 (2.0) | ||
N classification | 0.016 | ||||
N0 | 329 (66.3) | 115 (58.4) | 214 (71.6) | ||
N1 | 123 (24.8) | 59 (29.9) | 64 (21.4) | ||
N2 | 30 (6.0) | 17 (8.6) | 13 (4.3) | ||
N3 | 14 (2.8) | 6 (3.0) | 8 (2.7) | ||
AJCC stage | <0.001 | ||||
I | 200 (40.3) | 42 (21.3) | 158 (52.8) | ||
II | 252 (50.8) | 131 (66.5) | 121 (40.5) | ||
III | 44 (8.9) | 24 (12.2) | 20 (6.7) | ||
Histologic grade c | <0.001 | ||||
1 | 157 (35.0) | 43 (22.8) | 114 (44.0) | ||
2 | 199 (44.4) | 78 (41.3) | 121 (46.7) | ||
3 | 92 (20.5) | 68 (36.0) | 24 (9.3) | ||
ER | 0.001 | ||||
Positive | 304 (61.3) | 102 (51.8) | 202 (67.6) | ||
Negative | 192 (38.7) | 95 (48.2) | 97 (32.4) | ||
PR | 0.005 | ||||
Positive | 293 (59.1) | 97 (49.2) | 196 (65.6) | ||
Negative | 203 (40.9) | 100 (50.8) | 103 (34.4) | ||
HER-2 d | <0.001 | ||||
Positive | 127 (25.6) | 72 (36.5) | 55 (18.4) | ||
Negative | 369 (74.4) | 125 (63.5) | 244 (81.6) | ||
Ki67 | <0.001 | ||||
High | 102 (20.6) | 64 (32.5) | 38 (12.7) | ||
Low | 394 (79.4) | 133(67.5) | 261 (87.3) | ||
Subtypes | <0.001 | ||||
Luminal A | 257 (51.8) | 71 (36.0) | 186 (62.2) | ||
Luminal B | 71 (14.4) | 39 (19.8) | 32 (10.7) | ||
HER2 | 83 (16.7) | 45 (22.8) | 38 (12.7) | ||
Triple negative | 85 (17.1) | 42 (21.3) | 43 (14.4) | ||
Surgery type | 0.043 | ||||
Mastectomy | 352 (70.9) | 150 (76.1) | 202 (67.5) | ||
Breast-conserving surgery | 144 (29.1) | 47 (24.9) | 97 (32.5) | ||
Adjuvant chemotherapy | <0.001 | ||||
Yes | 347 (70.0) | 162 (82.2) | 185 (61.9) | ||
No | 149 (30.0) | 35 (17.8) | 114 (38.1) | ||
Adjuvant endocrine therapy | 0.001 | ||||
Yes | 332 (66.9) | 114 (57.9) | 218 (72.9) | ||
No | 164 (33.1) | 83 (42.1) | 81 (27.1) | ||
Adjuvant radiotherapy | 0.915 | ||||
Yes | 189 (38.1) | 74 (37.6) | 115 (38.5) | ||
No | 307 (61.9) | 123 (62.4) | 184 (61.5) | ||