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Table 2 Univariate and multivariate analysis of elafin-positive cells in luminal A-like breast cancer patients

From: Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence

A: Univariate analysis of clinicopatholoigal variable in luminal A patients (n = 343)

Factors

 

Elafin Negative (n = 185)

Elafin Positive (n = 158)

P value

Age at diagnosis, year

   

0.8

Mean

 

56.7

56.4

 

Median (range)

 

55 (26–84)

57 (29–87)

 

Stage

   

<0.0001

I

 

81 (44.0)

38 (24.2)

 

IIA

 

79 (42.9)

83 (52.9)

 

IIB

 

24 (13.0)

36 (22.9)

 

Unknown

 

1

1

 

Grade

   

0.001

I

 

31 (18.3)

15 (10.3)

 

II

 

122 (72.2)

96 (65.7)

 

III

 

16 (9.5)

35 (24.0)

 

Unknown

 

16

12

 

Recurrence

   

<0.0001

No

 

158 (86.3)

98 (62.4)

 

Yes

 

25 (13.7)

59(37.6)

 

Unknown

 

2

1

 

B: Multivariate of clinicopathologic variables’ influence on RFS in luminal A patients (n = 343)

Factor

HR

Se

P

95% CI

Age

0.97

0.01

<0.0001

0.95-0.98

Elafin positive

3

0.73

<0.0001

1.87-4.82